Journal article icon

Journal article

Notch signalling and the initiation of neural development in the Drosophila eye.

Abstract:

Neural determination in the Drosophila eye occurs progressively. A diffusible signal, Dpp, causes undetermined cells first to adopt a 'pre-proneural' state in which they are primed to start differentiating. A second signal is required to trigger the activation of the transcription factor Atonal, which causes the cells to initiate overt photoreceptor neurone differentiation. Both Dpp and the second signal are dependent on Hedgehog (Hh) signalling. Previous work has shown that the Notch signall...

Expand abstract
Publication status:
Published

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Development (Cambridge, England)
Volume:
128
Issue:
20
Pages:
3889-3898
Publication date:
2001-10-05
EISSN:
1477-9129
ISSN:
0950-1991
URN:
uuid:fcda05da-9e16-48da-a6bb-012cb8779748
Source identifiers:
356086
Local pid:
pubs:356086

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP