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Journal article

Role of the mitochondrial DNA 16184-16193 poly-C tract in type 2 diabetes.

Abstract:

Recent evidence suggests that polymorphic genetic variation in the non-coding region of mitochondrial DNA (the 16184-16193 polycytosine [poly-C] tract) contributes to the cause of type 2 diabetes, but previous studies only just reached significance. We aimed to investigate this association. We compared patients with type 2 diabetes (n=992) with two independent control groups (n=536, n=1029) from the UK, and saw no difference in the frequency of the 16184-16193 poly-C tract. This finding was c...

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Publication status:
Published

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Journal:
Lancet
Volume:
366
Issue:
9497
Pages:
1650-1651
Publication date:
2005-11-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:fcd4c4a1-e1b0-420e-8001-663e64efc7dc
Source identifiers:
29441
Local pid:
pubs:29441

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