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Unexpected maintenance of hepatitis C viral diversity following liver transplantation.

Abstract:

Chronic hepatitis C virus (HCV) infection can lead to liver cirrhosis in up to 20% of individuals, often requiring liver transplantation. Although the new liver is known to be rapidly reinfected, the dynamics and source of the reinfecting virus(es) are unclear, resulting in some confusion concerning the relationship between clinical outcome and viral characteristics. To clarify the dynamics of liver reinfection, longitudinal serum viral samples from 10 transplant patients were studied. Part o...

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Publication status:
Published

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Publisher copy:
10.1128/jvi.00749-12

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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
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Journal:
Journal of virology
Volume:
86
Issue:
16
Pages:
8432-8439
Publication date:
2012-08-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:fcd47584-4c93-40be-9826-8b779ac82e66
Source identifiers:
332843
Local pid:
pubs:332843

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