Journal article

Development and evaluation of a polygenic risk score for lung cancer in never-smoking women: a large-scale prospective Chinese cohort study

Abstract:: The proportion of lung cancer in never smokers is rising, especially among Asian women, but there is no effective early detection tool. Here, we developed a polygenic risk score (PRS), which may help to identify the population with higher risk of lung cancer in never-smoking women. We first performed a large GWAS meta-analysis (8595 cases and 8275 controls) to systematically identify the susceptibility loci for lung cancer in never-smoking Asian women and then generated a PRS using GWAS datas...
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Wei, X., Sun, D., Gao, J., Zhang, J., Zhu, M., Yu, C., Ma, Z., Fu, Y., Ji, C., Pei, P., Yang, L., Millwood, I. Y., Walters, R. G., Chen, Y., Du, H., Jin, G., Chen, Z., Hu, Z., Li, L., … Ma, H. (2023). Development and evaluation of a polygenic risk score for lung cancer in never-smoking women: a large-scale prospective Chinese cohort study. International Journal of Cancer, 154(5), 807–815.

MLA Style

Wei, X., et al. “Development and Evaluation of a Polygenic Risk Score for Lung Cancer in Never-Smoking Women: a Large-Scale Prospective Chinese Cohort Study.” International Journal of Cancer, vol. 154, no. 5, Wiley, 2023, pp. 807–15.

Chicago Style

Wei, X, D Sun, J Gao, J Zhang, M Zhu, C Yu, Z Ma, et al. 2023. “Development and Evaluation of a Polygenic Risk Score for Lung Cancer in Never-Smoking Women: a Large-Scale Prospective Chinese Cohort Study.” International Journal of Cancer 154 (5): 807–15.
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Publisher copy:: 10.1002/ijc.34765

Authors

+ Wei, X More by this author

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+ Sun, D More by this author

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+ Gao, J More by this author

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+ Zhang, J More by this author

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+ Zhu, M More by this author

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Funding

+ CAMS Innovation Fund for Medical Sciences More from this funder

Grant:

2019RU038

Bibliographic Details

Publisher:: Wiley
Journal:: International Journal of Cancer More from this journal
Volume:: 154
Issue:: 5
Pages:: 807-815
Place of publication:: United States
Publication date:: 2023-10-17
Acceptance date:: 2023-09-13
DOI:: 10.1002/ijc.34765
EISSN:: 1097-0215
ISSN:: 0020-7136
Pmid:: 37846649

Item Description

Language:: English
Keywords:: FFR

lung cancer in never-smoking women

polygenic risk score

predictive markers
Pubs id:: 1546095
Local pid:: pubs:1546095
Deposit date:: 2023-10-30

Terms of use

Copyright holder:: UICC
Copyright date:: 2023
Rights statement:: © 2023 UICC

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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