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Evidence for the regulation of left-right asymmetry in Ciona intestinalis by ion flux.

Abstract:

Vertebrate embryos develop distinct left-right asymmetry under the control of a conserved pathway involving left-sided deployment of the nodal and Pit x 2 genes. The mechanism that initiates asymmetric expression of these genes is less clear, with cilia, ion flux, and signalling molecules all implicated. Vertebrates share the chordate phylum with urochordates such as the sea squirt Ciona intestinalis. We have explored the role of ion flux in regulating left-right asymmetry in Ciona, using an ...

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Publication status:
Published

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Publisher copy:
10.1002/dvdy.20792

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
Journal:
Developmental dynamics : an official publication of the American Association of Anatomists More from this journal
Volume:
235
Issue:
6
Pages:
1543-1553
Publication date:
2006-06-01
DOI:
EISSN:
1097-0177
ISSN:
1058-8388
Language:
English
Keywords:
Pubs id:
pubs:209441
UUID:
uuid:fcc6e625-68b9-4046-a900-49b57d723a0a
Local pid:
pubs:209441
Source identifiers:
209441
Deposit date:
2013-11-16

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