- Abstract:
-
During early menopause, steady-state bone remodeling is perturbed; the number of basic multicellular units (BMUs) excavating cavities upon the endosteal surface exceeds the number (generated before menopause) concurrently refilling. Later in menopause, steady-state is restored; the many BMUs generated in early menopause refill as similarly large numbers of BMUs concurrently excavate new cavities. We hypothesized that risedronate reduces the number of cavities excavated. However, in younger po...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/jbmr.2101
-
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- Journal:
- Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
- Volume:
- 29
- Issue:
- 2
- Pages:
- 380-388
- Publication date:
- 2014-02-05
- DOI:
- EISSN:
-
1523-4681
- ISSN:
-
0884-0431
- URN:
-
uuid:fcc1a0e5-e994-4b47-8fc1-b4eda6b58b64
- Source identifiers:
-
473388
- Local pid:
- pubs:473388
- Copyright date:
- 2014
Journal article
Risedronate slows or partly reverses cortical and trabecular microarchitectural deterioration in postmenopausal women.
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