- Abstract:
-
Many peripheral solid tumors such as sarcomas and carcinomas express tumor-specific antigens that can serve as targets for immune effector T cells. Nevertheless, overall immune surveillance against such tumors seems relatively inefficient. We studied immune surveillance against a s.c. sarcoma expressing a characterized viral tumor antigen. Surprisingly, the tumor cells were capable of inducing a protective cytotoxic T cell response if transferred as a single-cell suspension. However, if they ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1073/pnas.96.5.2233
-
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- Journal:
- Proceedings of the National Academy of Sciences of the United States of America
- Volume:
- 96
- Issue:
- 5
- Pages:
- 2233-2238
- Publication date:
- 1999-03-05
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
- URN:
-
uuid:fcb0a541-776f-45aa-b04a-77630841cb11
- Source identifiers:
-
10739
- Local pid:
- pubs:10739
- Language:
- English
- Keywords:
- Copyright date:
- 1999
Journal article
Immune surveillance against a solid tumor fails because of immunological ignorance.
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