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Thesis

Development and application of genome-wide association studies in bacteria

Abstract:

Since the first genome-wide association study (GWAS) applied to humans in 2005, incredible advances have been made in understanding the genetic basis underlying common human diseases and complex traits. Dramatic technological developments have enabled rapid, inexpensive whole-genome sequencing in large numbers of bacteria, creating intense interest in the large-scale application of GWAS to bacteria. However, fundamental differences between the genomes of humans and bacteria mean that ...

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Department:
Nuffield Department of Medicine
Role:
Author, Copyright Holder

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Department:
Nuffield Department of Population Health
Role:
Copyright Holder, Examiner, Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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