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Journal article

The acute light-induction of sleep is mediated by OPN4-based photoreception.

Abstract:

Sleep is regulated by both homeostatic and circadian mechanisms. The latter, termed 'process c', helps synchronize sleep-wake patterns to the appropriate time of the day. However, in the absence of a circadian clock, overall sleep-wake rhythmicity is preserved and remains synchronized to the external light-dark cycle, indicating that there is an additional, clock-independent photic input to sleep. We found that the direct photic regulation of sleep in mice is predominantly mediated by melanop...

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Publication status:
Published

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Publisher copy:
10.1038/nn.2179

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
Nat Neurosci
Volume:
11
Issue:
9
Pages:
1068-1073
Publication date:
2008-08-17
DOI:
ISSN:
1546-1726
URN:
uuid:fc858c21-e8af-41d6-a22c-edabffdcc6fe
Source identifiers:
101541
Local pid:
pubs:101541
Language:
English

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