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HIV-1 pseudotype virus containing a Cocal virus genome and an HIV envelope: construction, assay and use.

Abstract:

A method is described for the production and assay of pseudotype viruses between human immunodeficiency virus type 1 (HIV-1) and Cocal virus (COV), containing an HIV-1 envelope and a COV genome (COV(HIV)). COV(HIV) pseudotype virus is a useful tool for the investigation of a variety of questions regarding HIV entry into susceptible cells, including steps in virus binding, fusion, and internalization, and the role of molecules which inhibit entry. COV, a rhabdovirus closely related to vesicula...

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Publication status:
Published

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Journal:
Journal of virological methods More from this journal
Volume:
44
Issue:
2-3
Pages:
287-304
Publication date:
1993-10-01
DOI:
EISSN:
1879-0984
ISSN:
0166-0934
Language:
English
Keywords:
Pubs id:
pubs:6090
UUID:
uuid:fc7edc7a-d947-460e-9952-86adf8994351
Local pid:
pubs:6090
Source identifiers:
6090
Deposit date:
2012-12-19

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