Journal article
Human pulmonary vascular response to 4 h of hypercapnia and hypocapnia measured using Doppler echocardiography.
- Abstract:
-
Hypercapnia has been shown in animal experiments to induce pulmonary hypertension. This study measured the sensitivity and time course of the human pulmonary vascular response to sustained (4 h) hypercapnia and hypocapnia. Twelve volunteers undertook three protocols: 1) 4-h euoxic (end-tidal Po(2) = 100 Torr) hypercapnia (end-tidal Pco(2) was 10 Torr above normal), followed by 2 h of recovery with euoxic eucapnia; 2) 4-h euoxic hypocapnia (end-tidal Pco(2) was 10 Torr below normal) followed b...
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- Publication status:
- Published
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- Publisher copy:
- 10.1152/japplphysiol.00890.2002
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Bibliographic Details
- Journal:
- Journal of applied physiology (Bethesda, Md. : 1985)
- Volume:
- 94
- Issue:
- 4
- Pages:
- 1543-1551
- Publication date:
- 2003-04-01
- DOI:
- EISSN:
-
1522-1601
- ISSN:
-
8750-7587
- Source identifiers:
-
114247
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:114247
- UUID:
-
uuid:fc5353ac-6d72-476a-b738-a58819357524
- Local pid:
- pubs:114247
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2003
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