Journal article icon

Journal article

Structural role of Sfi1p-centrin filaments in budding yeast spindle pole body duplication.

Abstract:

Centrins are calmodulin-like proteins present in centrosomes and yeast spindle pole bodies (SPBs) and have essential functions in their duplication. The Saccharomyces cerevisiae centrin, Cdc31p, binds Sfi1p on multiple conserved repeats; both proteins localize to the SPB half-bridge, where the new SPB is assembled. The crystal structures of Sfi1p-centrin complexes containing several repeats show Sfi1p as an alpha helix with centrins wrapped around each repeat and similar centrin-centrin conta...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1083/jcb.200603153

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Role:
Author
Journal:
Journal of cell biology More from this journal
Volume:
173
Issue:
6
Pages:
867-877
Publication date:
2006-06-01
DOI:
EISSN:
1540-8140
ISSN:
0021-9525

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP