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The pharmacokinetics of L-tryptophan following its intravenous and oral administration.

Abstract:

The pharmacokinetics of L-tryptophan (5 g and 7.5 g) have been studied after its intravenous administration to healthy subjects and the results compared with those obtained after oral administration (0.7 g-3.5 g). In order to do this, we have re-analysed previously published data relating to oral administration. The data obtained following the oral administration of L-tryptophan suggest that the total body clearance and apparent volume of distribution are saturable. The pharmacokinetics of tr...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
Journal:
British journal of clinical pharmacology More from this journal
Volume:
20
Issue:
4
Pages:
317-321
Publication date:
1985-10-01
DOI:
EISSN:
1365-2125
ISSN:
0306-5251
Language:
English
Keywords:
Pubs id:
pubs:185939
UUID:
uuid:fc3a4270-39df-41ea-aeb3-f0de16db5f0e
Local pid:
pubs:185939
Source identifiers:
185939
Deposit date:
2012-12-19

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