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Antimicrobial resistance following azithromycin mass drug administration: potential surveillance strategies to assess public health impact

Abstract:

The reduction in childhood mortality noted in trials investigating azithromycin mass drug administration (MDA) for trachoma control has been confirmed by a recent large randomized controlled trial. Population-level implementation of azithromycin MDA may lead to selection of multiresistant pathogens. Evidence suggests that repeated azithromycin MDA may result in a sustained increase in macrolide and other antibiotic resistance in gut and respiratory bacteria. Current evidence comes from standa...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1093/cid/ciz893

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Oxford college:
Nuffield College
Role:
Author
ORCID:
0000-0002-1236-849X
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Role:
Author
ORCID:
0000-0001-8699-8905
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Name:
Bill and Melinda Gates Foundation
Grant:
OPP1131320
Publisher:
Oxford University Press
Journal:
Clinical Infectious Diseases More from this journal
Volume:
70
Issue:
7
Pages:
1501-1508
Publication date:
2019-10-21
Acceptance date:
2019-09-05
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
Language:
English
Keywords:
Pubs id:
pubs:1064406
UUID:
uuid:fc296805-4d0c-4e75-9ae4-35f7c381068e
Local pid:
pubs:1064406
Source identifiers:
1064406
Deposit date:
2019-10-25

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