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Journal article : Review

The flagellum attachment zone: 'the cellular ruler' of trypanosome morphology

Abstract:

A defining feature of Trypanosoma brucei cell shape is the lateral attachment of the flagellum to the cell body, mediated by the flagellum attachment zone (FAZ). The FAZ is a complex cytoskeletal structure that connects the flagellum skeleton through two membranes to the cytoskeleton. The FAZ acts as a 'cellular ruler' of morphology by regulating cell length and organelle position and is therefore critical for both cell division and life cycle differentiations. Here we provide an overview of ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.pt.2015.12.010

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
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Name:
Wellcome Trust
Grant:
WT066839MA, 104627/Z/14/Z
Publisher:
Cell Press
Journal:
Trends in Parasitology More from this journal
Volume:
32
Issue:
4
Pages:
309–324
Publication date:
2016-03-30
DOI:
EISSN:
1471-5007
ISSN:
1471-4922
Language:
English
Keywords:
Subtype:
Review
Pubs id:
pubs:592511
UUID:
uuid:fc2046f4-ad87-4d0e-bd71-317a8a88dfcb
Local pid:
pubs:592511
Source identifiers:
592511
Deposit date:
2016-03-09

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