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Combination training in aging individuals modifies functional connectivity and cognition, and is potentially affected by dopamine-related genes

Abstract:

Background Aging is a major co-risk factor in many neurodegenerative diseases. Cognitive enrichment positively affects the structural plasticity of the aging brain. In this study, we evaluated effects of a set of structured multimodal activities (Combination Training; CT) on cognitive performances, functional connectivity, and cortical thickness of a group of healthy elderly individuals. CT lasted six months. Methodology Neuropsychological and occupational performances were evaluated before a...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0043901

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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
Publisher:
Public Library of Science
Journal:
PloS ONE More from this journal
Volume:
7
Issue:
8
Pages:
ARTN e43901
Publication date:
2012-08-28
Acceptance date:
2012-07-27
DOI:
EISSN:
1932-6203
Language:
English
Keywords:
Pubs id:
pubs:364100
UUID:
uuid:fc163ce1-29bd-41e3-9359-e7786bf5d467
Local pid:
pubs:364100
Source identifiers:
364100
Deposit date:
2013-11-16

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