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NAADP, a new intracellular messenger that mobilizes Ca2+ from acidic stores.

Abstract:

NAADP (nicotinic acid-adenine dinucleotide phosphate) is a recently described Ca2+-mobilizing molecule. First characterized in the sea urchin egg, it has been shown to mobilize Ca2+ from intracellular stores in a wide range of cells from different organisms. It is a remarkably potent molecule, and recent reports show that its cellular levels change in response to a variety of agonists, confirming its role as a Ca2+-mobilizing messenger. In many cases, NAADP appears to interact with other Ca2+...

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Publication status:
Published

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Publisher copy:
10.1042/bst0340922

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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology, BHF Centre of Research Excellence
Role:
Author
Journal:
Biochemical Society transactions
Volume:
34
Issue:
Pt 5
Pages:
922-926
Publication date:
2006-11-05
DOI:
EISSN:
1470-8752
ISSN:
0300-5127
URN:
uuid:fc0bb982-7671-4e7c-9899-1a9129f841e1
Source identifiers:
106539
Local pid:
pubs:106539

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