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pCT Derived Arterial Input Function for Improved Pharmacokinetic Analysis of Longitudinal dceMRI for Colorectal Cancer

Abstract:

Dynamic contrast-enhanced MRI is a dynamic imaging technique that is now widely used for cancer imaging. Changes in tumour microvasculature are typically quantified by pharmacokinetic modelling of the contrast uptake curves. Reliable pharmacokinetic parameter estimation depends on the measurement of the arterial in- put function, which can be obtained from arterial blood sampling, or extracted from the image data directly. However, arterial blood sampling poses additional risks to the patient...

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Publication status:
Published

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Publisher copy:
10.1117/12.2007036

Authors


Bhushan, M More by this author
Franklin, J More by this author
Anderson, EM More by this author
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Journal:
MEDICAL IMAGING 2013: IMAGE PROCESSING
Volume:
8669
Publication date:
2013
DOI:
ISSN:
0277-786X
URN:
uuid:fbde1018-91f0-4635-8411-05330814f08e
Source identifiers:
404109
Local pid:
pubs:404109

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