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Journal article

The circadian clock and viral infections

Abstract:

The circadian clock controls several aspects of mammalian physiology and orchestrates the daily oscillations of biological processes and behavior. Our circadian rhythms are driven by an endogenous central clock in the brain that synchronizes with clocks in peripheral tissues, thereby regulating our immune system and the severity of infections. These rhythms affect the pharmacokinetics and efficacy of therapeutic agents and vaccines. The core circadian regulatory circuits and clock-regulated h...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Target Discovery Institute
Role:
Author
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Name:
Wellcome Trust
Grant:
200838/Z/16/Z
More from this funder
Name:
Medical Research Council
Grant:
DJAA.RRAK21050
Publisher:
SAGE Publications
Journal:
Journal of Biological Rhythms More from this journal
Volume:
36
Issue:
1
Pages:
9-22
Publication date:
2020-11-09
Acceptance date:
2020-09-27
DOI:
EISSN:
1552-4531
ISSN:
0748-7304
Language:
English
Keywords:
Pubs id:
1138417
Local pid:
pubs:1138417
Deposit date:
2020-10-20

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