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SIMULTANEOUS DETERMINATION OF ARTEMETHER AND AZITHROMYCIN IN SUPPOSITORIES BY REVERSED PHASE HPLC

Abstract:

Chromatographic parameter assessments for RP-HPLC-UV method development for the simultaneous analysis of artemether and azithromycin for the pharmaceutical analysis of a rectal coformulation currently under development for the treatment of malaria infected children. Using methanol based mobile phase for the analysis of both artemether and azithromycin provided a more robust method in terms of resolution and peak symmetry. The method validated for suppository used 80% methanol and 20% phosphat...

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Publication status:
Published

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Authors


Gaubert, A More by this author
Dubost, J-P More by this author
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Journal:
ANALYTICAL LETTERS
Volume:
44
Issue:
16
Pages:
2732-2743
Publication date:
2011
DOI:
EISSN:
1532-236X
ISSN:
0003-2719
URN:
uuid:fbce1e9a-bbbe-4b2b-9c19-c4e139105749
Source identifiers:
206184
Local pid:
pubs:206184

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