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Journal article

Mirtrons, an emerging class of atypical miRNA.

Abstract:

Post-transcriptional gene silencing (PTGS) via RNA interference (RNAi) is a vital gene regulatory mechanism for fine-tuning gene expression. RNAi effectors termed microRNAs (miRNAs) are implicated in various aspects of animal development and normal physiological function, while dysregulation has been linked to several pathologies. Several atypical miRNA biogenesis pathways have been identified, yet in most cases the reasons for their emergence remain unclear. One of these atypical pathways is...

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Publisher copy:
10.1002/wrna.1122

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Wiley interdisciplinary reviews. RNA More from this journal
Volume:
3
Issue:
5
Pages:
617-632
Publication date:
2012-09-01
DOI:
EISSN:
1757-7012
ISSN:
1757-7004
Language:
English
Keywords:
Pubs id:
pubs:341140
UUID:
uuid:fbca1790-dc15-4ccc-87bf-1fe8c4000984
Local pid:
pubs:341140
Source identifiers:
341140
Deposit date:
2013-11-16

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