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Spirocyclic systems derived from pyroglutamic acid.

Abstract:
The synthesis and likely conformational structure of rigid spirocyclic bislactams and lactam-lactones derived from pyroglutamic acid, and their suitability as lead structures for applications in drug development programmes using cheminformatic analysis, has been investgated.
Publication status:
Published

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Publisher copy:
10.1039/c1ob05708a

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
Organic and biomolecular chemistry More from this journal
Volume:
9
Issue:
20
Pages:
7042-7056
Publication date:
2011-10-01
DOI:
EISSN:
1477-0539
ISSN:
1477-0520
Language:
English
Keywords:
Pubs id:
pubs:172067
UUID:
uuid:fbbc81ad-10ce-4581-aa02-2dc6b61d5c78
Local pid:
pubs:172067
Source identifiers:
172067
Deposit date:
2012-12-19

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