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Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon.

Abstract:

The CD44 cell surface glycoprotein is expressed on a broad range of different tissues as multiple isoforms containing from one to ten alternatively spliced exons v1-v10 inserted within the extracellular domain. Differential glycosylation generates still further variability, yielding both N- and O-glycan-modified forms of CD44 in addition to proteoglycan-like variants containing chondroitin sulphate and heparan sulphate. These high molecular mass proteoglycan-like variants, previously identifi...

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Publication status:
Published

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Publisher copy:
10.1083/jcb.128.4.673

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Journal:
Journal of cell biology More from this journal
Volume:
128
Issue:
4
Pages:
673-685
Publication date:
1995-02-01
DOI:
EISSN:
1540-8140
ISSN:
0021-9525

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