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Potential role of endothelial progenitor cells in the pathophysiology of heart failure: clinical implications and perspectives.

Abstract:

Endothelial dysfunction is thought to play a major role in the development and clinical complications of heart failure. Endothelial progenitor cells (EPCs) have been shown to provide an endogenous repair mechanism to counteract detrimental risk factor-induced effects and replace dysfunctional endothelium. The number and in vitro function of EPCs is altered in patients with heart failure, as a result of its pathophysiological mechanisms. EPCs could represent a substitutional marker to guide pr...

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Journal:
Atherosclerosis More from this journal
Volume:
189
Issue:
2
Pages:
247-254
Publication date:
2006-12-01
DOI:
EISSN:
1879-1484
ISSN:
0021-9150
Language:
English
Keywords:
Pubs id:
pubs:223228
UUID:
uuid:fb6fb219-8fa9-47e2-b6d1-4e7ec56afb43
Local pid:
pubs:223228
Source identifiers:
223228
Deposit date:
2012-12-19

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