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Journal article

Reduction of EEG theta power and changes in motor activity in rats treated with ceftriaxone

Abstract:

The glutamate transporter GLT-1 is responsible for the largest proportion of total glutamate transport. Recently, it has been demonstrated that ceftriaxone (CEF) robustly increases GLT-1 expression. In addition, physiological studies have shown that GLT-1 up-regulation strongly affects synaptic plasticity, and leads to an impairment of the prepulse inhibition, a simple form of information processing, thus suggesting that GLT-1 over-expression may lead to dysfunctions of large populations of n...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0034139

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
Publisher:
Public Library of Science
Journal:
PloS ONE More from this journal
Volume:
7
Issue:
3
Pages:
ART e34139
Publication date:
2012-03-30
Acceptance date:
2012-02-22
DOI:
EISSN:
1932-6203
Language:
English
Keywords:
Pubs id:
pubs:456101
UUID:
uuid:fb650028-a334-4a58-9575-9d650533f220
Local pid:
pubs:456101
Source identifiers:
456101
Deposit date:
2014-05-13

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