Journal article icon

Journal article

Genomic DNA methylation: the mark and its mediators.

Abstract:

Methylation of DNA at position five of the cytosine ring occurs at most CpG dinucleotides in the mammalian genome and is essential for embryonic viability. With several of the key proteins now known, it has become possible to approach the biological significance of this epigenetic system through both biochemistry and genetics. As a result, advances have been made in our understanding of the mechanisms by which DNA methylation is targeted to specific regions of the genome and interpreted by me...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1016/j.tibs.2005.12.008

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Journal:
Trends in biochemical sciences More from this journal
Volume:
31
Issue:
2
Pages:
89-97
Publication date:
2006-02-01
DOI:
ISSN:
0968-0004
Language:
English
Keywords:
Pubs id:
pubs:99948
UUID:
uuid:fb5b6af2-4e16-4e20-a2de-eeba9b8a56f9
Local pid:
pubs:99948
Source identifiers:
99948
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP