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Journal article

Are neuroendocrine tumours a feature of tuberous sclerosis? A systematic review.

Abstract:

Tuberous sclerosis complex (TSC) is an autosomal dominant multisystem disorder characterised by the development of multiple hamartomas in numerous organs. It is caused by mutations of two tumour suppressor genes, TSC1 on chromosome 9q34 and TSC2 on chromosome 16p13.3, which encode for hamartin and tuberin respectively. The interaction between these two proteins, the tuberin-hamartin complex, has been shown to be critical to multiple intracellular signalling pathways, especially those controll...

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Publication status:
Published

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Publisher copy:
10.1677/erc-08-0142
Journal:
Endocrine-related cancer More from this journal
Volume:
16
Issue:
1
Pages:
45-58
Publication date:
2009-03-01
DOI:
EISSN:
1479-6821
ISSN:
1351-0088
Language:
English
Keywords:
Pubs id:
pubs:138376
UUID:
uuid:fb45ced7-3e53-43b5-a5a0-624823e24b74
Local pid:
pubs:138376
Source identifiers:
138376
Deposit date:
2012-12-19

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