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The core of bluetongue virus binds double-stranded RNA.

Abstract:
Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff.
Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
Journal:
Journal of virology More from this journal
Volume:
76
Issue:
18
Pages:
9533-9536
Publication date:
2002-09-01
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
Language:
English
Keywords:
Pubs id:
pubs:22971
UUID:
uuid:fb343644-0136-4984-ba45-35a72fd6e8fe
Local pid:
pubs:22971
Source identifiers:
22971
Deposit date:
2012-12-19

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