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Randomized trials describing lung inflammation after pleurodesis with talc of varying particle size.

Abstract:

We report two trials describing whether talc pleurodesis with a mean particle size of less than 15 microm ("mixed" talc) produces more lung and systemic inflammation than tetracycline or "graded" talc (most particles < 10 microm were removed). First, 20 patients with malignant effusions received tetracycline or mixed talc. Changes in lung and systemic inflammation from lung clearance scans, oxygen saturations, and C-reactive protein from baseline to 48 hours after pleurodesis were recorded...

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Publisher copy:
10.1164/rccm.200311-1579oc

Authors


Maskell, NA More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology, Biomedical Research Centre, Experimental Medicine Division
Hedley, EL More by this author
Pengelly, G More by this author
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Journal:
American journal of respiratory and critical care medicine
Volume:
170
Issue:
4
Pages:
377-382
Publication date:
2004-08-05
DOI:
EISSN:
1535-4970
ISSN:
1073-449X
URN:
uuid:fb323431-5e7e-47cc-874a-8eae6a8413a4
Source identifiers:
9053
Local pid:
pubs:9053

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