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Cross immunity and vaccination against multiple microparasite strains.

Abstract:

We explore the equilibrium properties of a series of compartmental, ODE models describing the interaction between different strains of pathogen. The interaction is conceptualized as acting through shared antigens: infection and recovery from one strain leaves the host with a primed immune response against subsequent strains. The models consider the effect of this priming on susceptibility (the ability to be infected) and transmission (the ability to infect) in an SIR model. In these models, t...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Journal:
IMA journal of mathematics applied in medicine and biology More from this journal
Volume:
15
Issue:
3
Pages:
211-233
Publication date:
1998-09-01
ISSN:
0265-0746
Language:
English
Keywords:
Pubs id:
pubs:449651
UUID:
uuid:fb0d6135-08e6-4df7-a3a5-0216f55adcb3
Local pid:
pubs:449651
Source identifiers:
449651
Deposit date:
2014-02-26

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