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Journal article

Preferential loss of IL-2-secreting CD4+ T helper cells in chronic HCV infection.

Abstract:

Hepatitis C virus (HCV) becomes persistent in the majority of infected individuals. In doing so, the virus evades host adaptive immune responses, although the mechanisms responsible in this evasion are not clear. Several groups have demonstrated weak or absent HCV-specific CD4+ T cell responses during chronic HCV infection using proliferation assays and, more recently, class II tetramers. However, the functional status of HCV-specific CD4+ T cells in resolved and persistent infection is poorl...

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Publication status:
Published

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Publisher copy:
10.1002/hep.20669

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Journal:
Hepatology (Baltimore, Md.) More from this journal
Volume:
41
Issue:
5
Pages:
1019-1028
Publication date:
2005-05-01
DOI:
EISSN:
1527-3350
ISSN:
0270-9139
Language:
English
Keywords:
Pubs id:
pubs:22315
UUID:
uuid:fb0c58bf-0c4d-4353-8840-6fb40217646a
Local pid:
pubs:22315
Source identifiers:
22315
Deposit date:
2012-12-19

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