- Abstract:
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Investigation of the transient processes integral to neuronal function demands rapid and high-resolution imaging techniques over a large field of view, which cannot be achieved with conventional scanning microscopes. Here we describe a compact light sheet fluorescence microscope, featuring a 45° inverted geometry and an integrated photolysis laser, that is optimized for applications in neuroscience, in particular fast imaging of sub-neuronal structures in mammalian brain slices. We demonstrat...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
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(pdf, 870.7KB)
-
- Publisher copy:
- 10.1038/srep26317
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- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Scientific Reports Journal website
- Volume:
- 6
- Pages:
- Article: 26317
- Publication date:
- 2016-04-05
- DOI:
- ISSN:
-
2045-2322
- Pubs id:
-
pubs:615291
- URN:
-
uuid:fb0936cf-566b-4d86-9c06-7794b3d0aaec
- Source identifiers:
-
615291
- Local pid:
- pubs:615291
- Copyright holder:
- Yang et al.
- Copyright date:
- 2016
- Notes:
- This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0
Journal article
A compact light-sheet microscope for the study of the mammalian central nervous system
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Biotechnology and Biological Sciences Research Council
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Wellcome Trust
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