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Journal article

Sugar synthesis in a protocellular model leads to a cell signalling response in bacteria.

Abstract:

The design of systems with life-like properties from simple chemical components may offer insights into biological processes, with the ultimate goal of creating an artificial chemical cell that would be considered to be alive. Most efforts to create artificial cells have concentrated on systems based on complex natural molecules such as DNA and RNA. Here we have constructed a lipid-bound protometabolism that synthesizes complex carbohydrates from simple feedstocks, which are capable of engagi...

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Publication status:
Published

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Publisher copy:
10.1038/nchem.296

Authors


Gardner, PM More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Journal:
Nature chemistry
Volume:
1
Issue:
5
Pages:
377-383
Publication date:
2009-08-05
DOI:
EISSN:
1755-4349
ISSN:
1755-4330
URN:
uuid:fb02691f-4a59-40fa-b026-da7d790ea9f0
Source identifiers:
41357
Local pid:
pubs:41357

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