- Abstract:
-
Resident gut bacteria are constantly influencing the immune system. Yet the role of the immune system in shaping microbiota composition during an organism's lifespan has remained unclear. Experiments in mice have been inconclusive due to differences in husbandry schemes that led to conflicting results. We used Drosophila as a genetically tractable system with simpler gut bacterial population structure and streamlined genetic backgrounds and established cross schemes to address this issue. We ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 2.0MB)
-
- Publisher copy:
- 10.1534/genetics.116.190215
-
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- Funding agency for:
- Ligoxygakis, P
- Publisher:
- Genetics Society of America Publisher's website
- Journal:
- Genetics Journal website
- Volume:
- 206
- Issue:
- 2
- Pages:
- 889-904
- Publication date:
- 2017-06-05
- Acceptance date:
- 2017-03-31
- DOI:
- EISSN:
-
1943-2631
- ISSN:
-
0016-6731
- Pubs id:
-
pubs:690758
- URN:
-
uri:fb001e2e-3cff-4ede-8c67-c4931893fd29
- UUID:
-
uuid:fb001e2e-3cff-4ede-8c67-c4931893fd29
- Local pid:
- pubs:690758
- Language:
- English
- Keywords:
- Copyright holder:
- Mistry et al
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 Mistry et al. Available freely online through the author-supported open access option. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Journal article
Interaction between familial transmission and a constitutively active immune system shapes gut microbiota in Drosophila melanogaster.
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+ Biotechnology and Biological Sciences Research Council
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