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Investigation of host candidate malaria-associated risk/protective SNPs in a Brazilian Amazonian population.

Abstract:

The Brazilian Amazon is a hypo-endemic malaria region with nearly 300,000 cases each year. A variety of genetic polymorphisms, particularly in erythrocyte receptors and immune response related genes, have been described to be associated with susceptibility and resistance to malaria. In order to identify polymorphisms that might be associated with malaria clinical outcomes in a Brazilian Amazonian population, sixty-four human single nucleotide polymorphisms in 37 genes were analyzed using a Se...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0036692

Authors


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Institution:
University of Oxford
Role:
Author
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Name:
International Atomic Energy Agency (IAEA)
Funding agency for:
Kwiatkowski, D
Grant:
G19/9
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Name:
Medical Research Council
Funding agency for:
Kwiatkowski, D
Grant:
G19/9
More from this funder
Name:
Wellcome Trust Sanger Institute
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Name:
International Atomic Energy Agency
More from this funder
Name:
Wellcome Trust Centre for Human Genetics
Publisher:
Public Library of Science
Journal:
PloS one More from this journal
Volume:
7
Issue:
5
Article number:
e36692
Publication date:
2012-01-01
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Language:
English
Keywords:
Pubs id:
pubs:334967
UUID:
uuid:faf5932f-acd5-4121-96d0-865e1ec0023e
Local pid:
pubs:334967
Source identifiers:
334967
Deposit date:
2012-12-19

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