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Protocol for the PACE trial: A randomised controlled trial of adaptive pacing, cognitive behaviour therapy, and graded exercise as supplements to standardised specialist medical care versus standardised specialist medical care alone for patients with the chronic fatigue syndrome/ myalgic encephalomyelitis or encephalopathy

Abstract:

Background: Chronic fatigue syndrome (CFS, also called myalgic encephalomyelitis/encephalopathy or ME) is a debilitating condition with no known cause or cure. Improvement may occur with medical care and additional therapies of pacing, cognitive behavioural therapy and graded exercise therapy. The latter two therapies have been found to be efficacious in small trials, but patient organisations' surveys have reported adverse effects. Although pacing has been advocated by patient organisations,...

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Publisher copy:
10.1186/1471-2377-7-6

Authors


Sharpe, MC More by this author
Chalder, T More by this author
DeCesare, JC More by this author
Journal:
BMC Neurology
Volume:
7
Publication date:
2007-03-08
DOI:
EISSN:
1471-2377
URN:
uuid:fae5ba7c-83e4-4e02-a4b1-04e44e7a0a63
Source identifiers:
178498
Local pid:
pubs:178498
Language:
English

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