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CT with the hepatocyte-specific contrast medium FP 736-04 in an experimental model of liver steatosis.

Abstract:

PURPOSE: To investigate whether liver uptake of the iodinated hepatocyte-specific lipid emulsion FP 736-04 is altered by fatty infiltration of the liver. MATERIAL AND METHODS: Fatty infiltration of the liver was induced in female Sprague-Dawley rats by an intraperitoneal injection of L-ethionine preceded by 15 h of food withdrawal. CT of the liver was performed before and 24 h after the administration of L-ethionine and, in addition at the latter time point, after an i.v. injection of 1.0 ml/...

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Publication status:
Published

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Publisher copy:
10.1080/02841859709172091

Authors


Bergman, A More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
Magnusson, A More by this author
Journal:
Acta radiologica (Stockholm, Sweden : 1987)
Volume:
38
Issue:
3
Pages:
405-409
Publication date:
1997-05-05
DOI:
EISSN:
1600-0455
ISSN:
0284-1851
URN:
uuid:fad49e1f-178b-4fba-8fa3-d93121cab8b9
Source identifiers:
22639
Local pid:
pubs:22639

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