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Journal article

Effectiveness of SMS 201-995, a synthetic, long-acting somatostatin analogue, in treatment of quinine-induced hyperinsulinaemia.

Abstract:

SMS 201-995, a new long-acting, synthetic somatostatin analogue, dose 50 micrograms/h, given as a continuous intravenous infusion, completely abolished quinine-induced insulin release in 9 healthy Thai volunteers. Hyperinsulinaemia, which caused sustained hypoglycaemia in a 32-year-old post-partum Thai patient who was receiving intravenous quinine for falciparum malaria, was suppressed within 30 min of starting SMS 201-995, and the patient became fully conscious. This octapeptide antagonises ...

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Publication status:
Published

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Journal:
Lancet More from this journal
Volume:
1
Issue:
8483
Pages:
713-716
Publication date:
1986-03-01
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Language:
English
Keywords:
Pubs id:
pubs:61082
UUID:
uuid:fac87419-3874-4f23-94ae-4188a3f4339e
Local pid:
pubs:61082
Source identifiers:
61082
Deposit date:
2012-12-19

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