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Prognostic impact of activated B-cell focused classification in diffuse large B-cell lymphoma patients treated with R-CHOP.

Abstract:

Gene expression profiling studies initially enabled diffuse large B-cell lymphoma to be divided into germinal center and activated B-cell-like subtypes, which define high- and low-risk patient groups when treated with chemotherapy. Attempts to reproduce the prognostic classification immunohistochemically have, however, provided inconsistent results. The aim of this study was to determine whether modified immunohistochemical classification of cell of origin focusing on activated B-cell-like ma...

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Publisher copy:
10.1038/modpathol.2009.73
Journal:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc More from this journal
Volume:
22
Issue:
8
Pages:
1094-1101
Publication date:
2009-08-01
DOI:
EISSN:
1530-0285
ISSN:
0893-3952

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