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Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group

Abstract:

Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understood. Structural brain differences have been associated with BD, but results from neuroimaging studies have been inconsistent. To address this, we performed the largest study to date of cortical gray matter thickness and surface area measures from brain magnetic resonance imaging scans of 6503 individuals including 1837 unrelated adults with BD and 2582 unrelated healthy controls for group differ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/mp.2017.73

Authors


Westlye, LT More by this author
Jahanshad, N More by this author
Cheung, JW More by this author
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Publisher:
Springer Nature Publisher's website
Journal:
Molecular Psychiatry Journal website
Volume:
23
Pages:
932–942
Publication date:
2017-05-02
DOI:
EISSN:
1476-5578
ISSN:
1359-4184
Pubs id:
pubs:692341
URN:
uri:faa77fa3-c0d7-4128-92d5-e63361cb3b8c
UUID:
uuid:faa77fa3-c0d7-4128-92d5-e63361cb3b8c
Local pid:
pubs:692341
Language:
English

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