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Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate.

Abstract:
The design of a range of 4-position-modified D-myo-inositol 1,4,5-trisphosphate derivatives is described. The enantioselective synthesis of these compounds is reported, along with initial biological analysis, which indicates that these compounds do not act as D-myo-inositol 1,4,5-trisphosphate receptor agonists or antagonists.
Publication status:
Published

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Publisher copy:
10.1021/jo070611a

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Journal:
Journal of organic chemistry More from this journal
Volume:
72
Issue:
15
Pages:
5647-5659
Publication date:
2007-07-01
DOI:
EISSN:
1520-6904
ISSN:
0022-3263
Language:
English
Keywords:
Pubs id:
pubs:52013
UUID:
uuid:fa80ee60-0cc1-4777-a6f0-ae633186e5a0
Local pid:
pubs:52013
Source identifiers:
52013
Deposit date:
2012-12-19

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