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Metabolic age based on the BBMRI-NL 1H-NMR metabolomics repository as biomarker of age-related disease

Abstract:

BACKGROUND: The blood metabolome incorporates cues from the environment and the host's genetic background, potentially offering a holistic view of an individual's health status.

METHODS: We have compiled a vast resource of proton nuclear magnetic resonance metabolomics and phenotypic data encompassing over 25 000 samples derived from 26 community and hospital-based cohorts.

RESULTS: Using this resource, we constructe... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1161/circgen.119.002610

Authors


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Role:
Author
ORCID:
0000-0002-7693-0728
More by this author
Role:
Author
ORCID:
0000-0003-0585-6206
Publisher:
American Heart Association
Journal:
Circulation More from this journal
Volume:
13
Issue:
5
Pages:
541-547
Publication date:
2020-08-14
Acceptance date:
2020-07-27
DOI:
EISSN:
2574-8300
ISSN:
2574-8300
Pmid:
33079603
Language:
English
Keywords:
Pubs id:
1140398
Local pid:
pubs:1140398
Deposit date:
2020-12-02

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