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The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis

Abstract:
Background Chloroquine remains the mainstay of treatment for Plasmodium vivax malaria despite increasing reports of treatment failure. We did a systematic review and meta-analysis to investigate the effect of chloroquine dose and the addition of primaquine on the risk of recurrent vivax malaria across different settings. Methods A systematic review done in MEDLINE, Web of Science, Embase, and Cochrane Database of Systematic Reviews identified P vivax clinica... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/s1473-3099(18)30348-7

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Role:
Author
More from this funder
Name:
Wellcome Trust
Funding agency for:
White, NJ
Price, RN
Grant:
Principal Fellow
Senior Fellow in Clinical Science (200909)
200909/Z/16/Z
More from this funder
Name:
Bill and Melinda Gates Foundation
Grant:
OPP1164105 and OPP1054404
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Name:
Tropical Network Fund, Nuffield Department of Clinical Medicine, University of Oxford
Funding agency for:
Dahal, P
More from this funder
Name:
Australian National Health and Medical Research Council
Publisher:
Elsevier
Journal:
Lancet Infectious Diseases More from this journal
Volume:
18
Issue:
9
Pages:
1025-1034
Publication date:
2018-07-19
Acceptance date:
2018-05-21
DOI:
ISSN:
1473-3099
Pmid:
30033231
Language:
English
Pubs id:
pubs:891099
UUID:
uuid:fa62d641-3262-4cb0-afcd-1d257ed3d9f7
Local pid:
pubs:891099
Source identifiers:
891099
Deposit date:
2018-07-26

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