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Journal article

The graft-versus-leukemia effect in AML

Abstract:

Allogeneic hematopoietic stem cell transplantation (allo-SCT) is the most established and commonly used cellular immunotherapy in cancer care. It is the most potent anti-leukemic therapy in patients with acute myeloid leukemia (AML) and is routinely used with curative intent in patients with intermediate and poor risk disease. Donor T cells, and possibly other immune cells, eliminate residual leukemia cells after prior (radio)chemotherapy. This immune-mediated response is known as graft-versu...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fonc.2019.01217

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
Weatherall Institute of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Strategic
Oxford college:
St Anne's College
Role:
Author
ORCID:
0000-0003-3931-0914
Publisher:
Frontiers Media
Journal:
Frontiers in Oncology More from this journal
Volume:
9
Article number:
1217
Publication date:
2019-11-19
Acceptance date:
2019-10-24
DOI:
ISSN:
2234-943X
Pmid:
31803612
Language:
English
Keywords:
Pubs id:
pubs:1077324
UUID:
uuid:fa562aba-e3d9-4af7-9543-8d0fd6439ad0
Local pid:
pubs:1077324
Source identifiers:
1077324
Deposit date:
2019-12-17

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