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Journal article

Animal models of multiple myeloma

Abstract:

Multiple myeloma (MM) is a plasma cell neoplasm which is defined by strong interactions with the bone marrow microenvironment, a compartment with high cellular heterogeneity and unique structural and extracellular components. This necessitates the use of in vivo models for research to fully recapitulate MM growth conditions. The selection of appropriate model system is crucial, as each has advantages and shortcomings. Here, we describe the murine models available for studying MM, and focus on...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Subgroup:
Botnar Research Centre
Oxford college:
St Edmund Hall
Role:
Author
ORCID:
0000-0002-1257-5659
Publisher:
Springer Publisher's website
Journal:
Methods in Molecular Biology Journal website
Volume:
1914
Pages:
349-360
Publication date:
2019-02-08
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
Pubs id:
pubs:969616
URN:
uri:fa4c8bb9-833f-49fe-9e04-22ff78bb9a06
UUID:
uuid:fa4c8bb9-833f-49fe-9e04-22ff78bb9a06
Local pid:
pubs:969616

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