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Journal article

Association between telomere length and risk of cancer and non-neoplastic diseases: A Mendelian randomization study.

Abstract:

Importance

The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation.

Objective

To conduct a Mendelian randomization study, using germline genetic variants as instrumental variables, to appraise the causal relevance of telomere length for risk of cancer and non-neoplastic diseases.

Da...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1001/jamaoncol.2016.5945

Authors


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Medical Research Council More from this funder
Bristol Nutritional Biomedical Research Unit More from this funder
National Institute for Health Research More from this funder
University of Bristol More from this funder
Publisher:
American Medical Association Publisher's website
Journal:
JAMA Oncology Journal website
Volume:
3
Issue:
5
Pages:
636-651
Publication date:
2017-02-01
Acceptance date:
2016-10-21
DOI:
EISSN:
2374-2445
ISSN:
2374-2437
Language:
English
Keywords:
Pubs id:
pubs:681995
UUID:
uuid:fa418653-b9ce-4f1f-bc60-a388ffad4b6b
Local pid:
pubs:681995
Deposit date:
2017-04-07

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