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Journal article

Association between telomere length and risk of cancer and non-neoplastic diseases: A Mendelian randomization study.

Abstract:

Importance

The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation.

Objective

To conduct a Mendelian randomization study, using germline genetic variants as instrumental variables, to appraise the causal relevance of telomere length for risk of cancer and non-neoplastic diseases.

Da...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1001/jamaoncol.2016.5945

Authors


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National Institute for Health Research More from this funder
Bristol Nutritional Biomedical Research Unit More from this funder
University of Bristol More from this funder
Publisher:
American Medical Association Publisher's website
Journal:
JAMA Oncology Journal website
Volume:
3
Issue:
5
Pages:
636-651
Publication date:
2017-02-05
Acceptance date:
2016-10-21
DOI:
EISSN:
2374-2445
ISSN:
2374-2437
Pubs id:
pubs:681995
URN:
uri:fa418653-b9ce-4f1f-bc60-a388ffad4b6b
UUID:
uuid:fa418653-b9ce-4f1f-bc60-a388ffad4b6b
Local pid:
pubs:681995
Language:
English
Keywords:

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