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Journal article

Association between telomere length and risk of cancer and non-neoplastic diseases: A Mendelian randomization study.

Abstract:

Importance

The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation.

Objective

To conduct a Mendelian randomization study, using germline genetic variants as instrumental variables, to appraise the causal relevance of telomere length for risk of cancer and non-neoplastic diseases.

Da...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


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Name:
Cancer Research UK
Grant:
C52724/A20138
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Name:
National Institute for Health Research
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Name:
Bristol Nutritional Biomedical Research Unit
Publisher:
American Medical Association
Journal:
JAMA Oncology More from this journal
Volume:
3
Issue:
5
Pages:
636-651
Publication date:
2017-02-01
Acceptance date:
2016-10-21
DOI:
EISSN:
2374-2445
ISSN:
2374-2437
Language:
English
Keywords:
Pubs id:
pubs:681995
UUID:
uuid:fa418653-b9ce-4f1f-bc60-a388ffad4b6b
Local pid:
pubs:681995
Deposit date:
2017-04-07

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