- Abstract:
-
Demographic and family studies support the existence of a genetic contribution to the pathogenesis of IgA nephropathy, but results from genetic association studies of candidate genes are inconsistent. To systematically survey common genetic variation in this disease, we performed a genome-wide analysis in a cohort of patients with IgA nephropathy selected from the UK Glomerulonephritis DNA Bank. We used two groups of controls: parents of affected individuals and previously genotyped, unaffect...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1681/asn.2010010076
-
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- Journal:
- Journal of the American Society of Nephrology : JASN
- Volume:
- 21
- Issue:
- 10
- Pages:
- 1791-1797
- Publication date:
- 2010-10-05
- DOI:
- EISSN:
-
1533-3450
- ISSN:
-
1046-6673
- URN:
-
uuid:fa3f70e3-cafb-4d7d-bd81-38f9a274b687
- Source identifiers:
-
74020
- Local pid:
- pubs:74020
- Copyright date:
- 2010
Journal article
HLA has strongest association with IgA nephropathy in genome-wide analysis.
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