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Journal article

Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.

Abstract:

CONTEXT: Variation in the region of chromosome 8 including the genes steroid 11beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) influences mineralocorticoid and glucocorticoid metabolism. However, the relative importance of polymorphisms in CYP11B1 and CYP11B2 in determining these phenotypes is unknown. OBJECTIVE: Our objective was to investigate genetic influences of the CYP11B1 and CYP11B2 genes on mineralocorticoid metabolism. DESIGN: We measured 24-h urinary excretion of the ...

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Publication status:
Published

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Publisher copy:
10.1210/jc.2006-1481

Authors


Mayosi, BM More by this author
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Journal:
The Journal of clinical endocrinology and metabolism
Volume:
91
Issue:
12
Pages:
5051-5056
Publication date:
2006-12-05
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
URN:
uuid:fa30b2ea-31d5-4288-8c74-14de3e96f89b
Source identifiers:
104368
Local pid:
pubs:104368

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