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Thesis

Ex vivo expansion of human IL-10+ B cells with regulatory function

Abstract:

Introduction: Solid organ transplantation is the gold standard therapy for many end-stage organ diseases. Although short-term graft survival is excellent due to the use of potent immunosuppressive regimens, incidence of chronic allograft dysfunction and graft failure remains unchanged. Global immunosuppressants are also associated with adverse side effects including severe infection, malignancy and target end-organ damage. Novel, targeted approaches are required to more effective...

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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author

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Role:
Supervisor
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Funding agency for:
Shankar, S
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:fa041dce-0095-4d0f-8089-5e7103124e02
Deposit date:
2017-05-07

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