Noxious somatosensory stimulation affects the default mode of brain function: evidence from functional MR imaging.
PURPOSE: To investigate whether default mode network (DMN) spatial properties can be directly affected by pain, with a comparison of painful and nonpainful conditions. MATERIALS AND METHODS: The authors performed a functional magnetic resonance (MR) imaging study, approved by the local institutional ethics committee, involving 10 healthy male subjects (age range, 18-45 years) who gave written informed consent. The subjects underwent two experimental sessions of median nerve electrical stimula...Expand abstract
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